DSpace Community:http://hdl.handle.net/11607/17972024-03-29T13:39:59Z2024-03-29T13:39:59ZYaygın lenfadenopati nedeni ile başvuran hastada sistemik lupus eritematozis tanısı: olgu sunumuTürkbeyler, İbrahim HalilPehlivan, YavuzÇömez, GaziZengin, OrhanGöktepe, FatihOnat, Ahmet Mesuthttp://hdl.handle.net/11607/22892016-03-10T01:01:23Z2011-01-01T00:00:00ZTitle: Yaygın lenfadenopati nedeni ile başvuran hastada sistemik lupus eritematozis tanısı: olgu sunumu
Authors: Türkbeyler, İbrahim Halil; Pehlivan, Yavuz; Çömez, Gazi; Zengin, Orhan; Göktepe, Fatih; Onat, Ahmet Mesut
Abstract: Lenfadenopati (LAP), lenf dügümünün boyut ve karakterindeki anormallik olarak tanımlanır. Lenfadenopati
neoplastik veya inflamatuar hücrelerin lenf nodunda çogalması veya lenf nodunu invazyonu sonucu olusabilir.
Lenfadenopati genis bir hastalık tablosu sonucunda gelisebilir. Yaygın lenfadenopati sebepleri arasında
enfeksiyonlar, otoimmun hastalıklar, malignensiler, histiyositozlar, depo hastalıkları, hiperplaziler ve ilaç
etkilesimleri sayılabilir. Lenfadenopati etyolojisinde kollajen doku hastalıkları önemli yer tutmaktadır. En sık
lenfadenopatiye neden olan otoimmun hastalıklar romatoid artrit, sistemik lupus eritematozis (SLE) ve Sjögren
sendromudur. Bu olguda yaygın lenfadenopati nedeni ile arastırılan ve SLE tanısı alan bir olguyu sunduk.
Lenfadenopati nedeniyle tetkik edilen hastalarda kollajen doku hastalıklarını ve özellikle de SLE'u göz önünde
bulundurmamız gerektigini bu yazıda vurgulamak istedik.; Lymphadenopathy (LAP) is defined as the abnormality in the size and character of lymph node.
Lymphadenopathy emerges due to increase of inflammatory cells in lymph node or invasion of these cells in the
lymph node. Lymphadenopathy may occur in any age group, in symptomatic or asymptomatic patients, and in a
single site or at multiple sites. Causes of generalized lymphadenopathy include infections, autoimmune diseases,
malignancies, histiocytoses, storage diseases, benign hyperplasia, and drug reactions. In LAP etiology, collagen
tissue disorders hold an important place. The most common autoimmune causes of LAPare rheumatoid arthritis,
systemic lupus erythematosus (SLE) and Sjogren syndrome. In this case, we presented a case which was
investigated for generalized lymphadenopathy and diagnosed with SLE. SLE diagnosis should be considered in
patients researched for lymphadenopathy etiology.2011-01-01T00:00:00ZMemede karsinosarkom olgusuTaşkın, FüsunÖzbaş, SerdarErkuş, Muhanhttp://hdl.handle.net/11607/22882016-03-10T01:01:22Z2011-01-01T00:00:00ZTitle: Memede karsinosarkom olgusu
Authors: Taşkın, Füsun; Özbaş, Serdar; Erkuş, Muhan
Abstract: Meme karsinosarkomu, sarkom benzeri bileseni bulunan duktal tip karsinomayı ifade eden, malin epitelyal ve
malin mezenkimal elemanların bir arada bulundugu bir malinitedir. Glandüler epitelin glandüler olmayan
mezensimal dokuya farklanmasıyla ortaya çıkan ve seyrek görülen metaplastik meme kanserlerinin en seyrek
görülen alt tipidir. Tüm meme malinitelerinin %1'inden azını olusturur. Literatürde karsinosarkomun radyolojik
özelliklerinin degerlendirildigi sınırlı sayıda çalısma bulunmaktadır. Hastanemiz meme hastalıkları poliklinigine
sol memede ele gelen kitle yakınmasıyla basvuran 44 yasında kadın hastada fizik bakı, mamografi ve
ultrasonografi bulguları degerlendirildi. Mamografi ve ultrasonografide lobüle, karma solid ve kistik alanlar
içeren kitle izlendi. Histopatolojik olarak karsinosarkom tanısı alan olguda parsiyel mastektomi ve aksiller
diseksiyon yapıldı. Aksilladan çıkartılan 16 lenf nodunun biri metastatikti ve uzak metastaz saptanmadı. Bizim
amacımız, nadir görülen bu tümörlerde radyolojik bulguları tanımlamak ve literatürü gözden geçirmektir; Carcinosarcoma of the breast represents a ductal carcinoma which consists sarcoma like component. Both malign
epithelial and malign mesenchymal elements exist together in the breast carcinosarcoma. Glandular epithelium
differentiates into non-glandular mesenchymal tissue, a process called metaplasia. Metaplastic breast
malignancy is a rare type of the breast cancer, moreover carcinosarcoma is the rarest subtype which is less than
1%of the whole breast cancers. There are limited studies and case reports of carcinosarcoma in literature. Fourtyfour
aged woman applied to breast diseases polyclinic with palpable mass on her left breast. We evaluated the
findings of the physical examination, mammography and ultrasound. On radiological evaluation we determined a
lobulated complex mass with solid and cystic components. Histopathological examination resulted as
carcinosarcoma. Lumpectomy and axillary dissection were performed. One axillary lymph node was metastatic
out of 16 lymph nodes. There were no distant metastases. Our purpose is to define the radiologic findings about
this rare tumour and to review the literature.2011-01-01T00:00:00ZPsikiyatrik bulgular ile prezente olan hipoglisemi ile ilişkili korpus kallosum infarktı: olgu sunumuGüler, SibelAygün, Murat Serhathttp://hdl.handle.net/11607/20842016-02-26T01:00:56Z2011-01-01T00:00:00ZTitle: Psikiyatrik bulgular ile prezente olan hipoglisemi ile ilişkili korpus kallosum infarktı: olgu sunumu
Authors: Güler, Sibel; Aygün, Murat Serhat
Abstract: A 54 years old female patient, presenting with psychiatric symptoms, after which corpus callosum infarct was detected is presented with the clinical, laboratory and radiological findings here. The patient, who did not have any psychiatric complaints before was evaluated because of personality changes and sleepy state starting 3 days before and disturbance in gait and speech of one day's duration. Previously she had a diagnosis of diabetes mellitus. Blood glucose was 45 mg/dL. An increase in signal intensity reciprocal to ADC in the corpus callosum was detected in cerebral diffusion magnetic resonance imaging (MRI). The psychiatric findings in this case were considered as “acute and temporary schizoid personality disorder” that may be explained by an underlying organic cause according to DSM-IV. The clinical symptoms that arise from corpus callosum abnormalities are variable. A psychiatric picture develops in approximately one thirds of the cases. On the other hand, corpus callosum infarct presenting with pure psychiatric findings are rarely observed in the literature. This case was considered interesting because of the temporal association between corpus callosum infarct and psychiatric symptoms in the context of coexistent hypoglycemia and left anterior cerebral artery occlusion.2011-01-01T00:00:00ZNon-sirotik portal hipertansiyonun nadir bi nedeni : primer antifosfolipid sendromuUlaş, TurgayBes, CemalGültürk, EmineNamal, EsatPaksoy, FatmaGürbüz, Didem GökçenBorlu, Fatihhttp://hdl.handle.net/11607/20802016-02-26T01:01:00Z2011-01-01T00:00:00ZTitle: Non-sirotik portal hipertansiyonun nadir bi nedeni : primer antifosfolipid sendromu
Authors: Ulaş, Turgay; Bes, Cemal; Gültürk, Emine; Namal, Esat; Paksoy, Fatma; Gürbüz, Didem Gökçen; Borlu, Fatih
Abstract: The antiphospholipid syndrome involves long-term persistence of serum antiphospholipid antibodies and hypercoagulability manifested by venous or arterial thrombosis, recurrent pregnancy loss or thrombocytopenia. Two forms have been described: the “primary syndrome” where there is no evidence of an underlying disease, and the “secondary syndrome”, mainly in the setting of systemic lupus eryhematosus. Classic features of antiphospholipid syndrome include cutaneous signs, such as livedo reticularis, splinter hemorrhages, superficial thrombophlebitis, and leg ulcers; venous thrombotic events, such as cerebral or retinal vein thrombosis; arterial thrombotic events, such as transient attacks or ischemic infarcts, recurrent spontaneous early-term abortions, and thrombocytopenia. Also various hepatic manifestations have been reported with antiphospholipid syndrome in literature, including Budd-Chiari syndrome, hepatic-veno-occlusive disease and occlusion of small hepatic veins, nodular regenerative hyperplasia and portal hypertension. Herein we present a case of non-cirrhotic portal hypertension associated with primary antiphospholipid syndrome which this coexisting is rarely seen in the literature.2011-01-01T00:00:00Z